Niveau d'étude
Bac +5
ECTS
6 crédits
Composante
UFR Chimie-Biologie
Période de l'année
Toute l'année
Description
Course outline
The lectures present the basic methodology and some advanced techniques used for high throughput in vitro small molecule drug discovery. The principles and statistical methods used for assay optimization and validation will also be explained.
I. Molecular biology, Biochemistry and Protein expression
II. Proteomic analysis; Mass spectrometry
III. Lab-chips and Cell-chips
IV. Structural biology: Crystallogenesis and Crystallization; RMN
V. Combinatory chemistry
Format of exams: Oral exam (at the end of December) and Research project (at the beginning of January)
Heures d'enseignement
- CMCM36h
Pré-requis recommandés
Background in biochemistry, molecular biology and cellular biology. Knowledge in physiology, immunology and microbiology will be appreciated. Students with laboratory and/or practical skills will better understand technological benefits of the use of high throughput technologies in the lab work.
Période
Semestre 9