Degrees incorporating this pedagocial element :
Description
Course outline
The lectures present the basic methodology and some advanced techniques used for high throughput in vitro small molecule drug discovery. The principles and statistical methods used for assay optimization and validation will also be explained.
I. Molecular biology, Biochemistry and Protein expression
II. Proteomic analysis; Mass spectrometry
III. Lab-chips and Cell-chips
IV. Structural biology: Crystallogenesis and Crystallization; RMN
V. Combinatory chemistry
Format of exams: Oral exam (at the end of December) and Research project (at the beginning of January)
Recommended prerequisite
Background in biochemistry, molecular biology and cellular biology. Knowledge in physiology, immunology and microbiology will be appreciated. Students with laboratory and/or practical skills will better understand technological benefits of the use of high throughput technologies in the lab work.
In brief
Period : Semester 9Credits : 6
Number of hours
- Tutorials (TD) : 10h
- Lectures (CM) : 30h
Location(s) : Grenoble
Language(s) : English
Contact(s)
Adrien ANTKOWIAK