UE Drug action and drug design

The course will aim at giving, through examples of existing drugs, an overview of the strategies used for drug development, from the identification of a molecular target to the marketing of an active product. The course will include presentations about enzyme catalysis and enzyme kinetics with particular emphasis on inhibition, on the problems faced when developing a drug and on computational approaches used in this field. The course will include sessions of computer analysis of enzyme kinetic data and of tutorials of molecular modeling.

Biochemistry (L3) (keywords: structure of the macromolecules, protein function, enzymology) 

Understanding the theoretical and experimental concepts of enzyme catalysis and enzyme kinetics, acquiring initial bases in computational methods for drug design and drug screening.