UE Molecular bases of the normal and pathological memory

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Degrees incorporating this pedagocial element :


The goal of this course is to apprehend the latest findings about the cellular and molecular mechanisms of synaptic plasticity and the causes of their impairment in neurodegenerative diseases with a special emphasis on Alzheimer’s disease.

  • What makes the electric      signal? The chemical synapse.
  • The glutaminergic synaps: plasticity and memory. Regulation of neurotransmitter disease, of post-synaptic currents, modulation of the expression of pre-and post-synaptic receptors.
  • Traffic and diffusion of synaptic receptors
  • Genetic and molecular causes of Alzheimer’s disease: presinilins, APP, ApoE. Fronto-temporal dementia.