UE Thermodynamics, transport and fluctuations: from nanomaterials to biologic systems

Diplômes intégrant cet élément pédagogique :


Goal: To introduce the basic statistical physics and thermodynamic concepts to address the equilibrium and evolution properties of nano-scale systems.

Content: The course will start from a thermodynamic view of materials, justified by microscopic models. It will explore the rich physics and physical-chemistry that governs the formation of complex nanostructured materials, from metallic alloys to polymers and other self-organized soft matter systems. The extension to biological systems will provide examples  in which these notions can be extended to non-equilibrium situations.

 I. Equilibrium and non-equilibrium effects in materials and nanomaterials
-Thermodynamics and phase diagrams
-Thermodynamics of heterogeneous systems and interfaces
-Heat and mass transport  in condensed systems
-Dynamics of phase transitions: nucleation and growth, spinodal decomposition
-Notions on numerical models: particle based models, PDEs
-Elements of stochastic thermodynamics

II. Biological matter: A statistical view of biological dynamics
-Application of random walks in Biology , Fick's law, solutions to the Diffusion equation (Frap, FCS), Rate equations (diffusion limited versus reaction limited regime), single molecule experiments on Biopolymers and Biomolecules (DNA, actin, ligand-receptor binding etc...).
-Two-state systems and cooperativity.
- Dynamics of molecular motors (rectified Brownian motion, polymerization Ratchets)
- Physics for the cell architecture and skeletons (beam theory, membrane mechanics, thermal fluctuations and mechanics, persistence length)
- Life at low Reynolds number

Informations complémentaires

Langue(s) : Français