UE Microbiology




- Regulatory networks and bacterial adaptation to the environment :

  • The stringent response
  • DNA topology-mediated control of gene expression

- Next-generation sequencing: Tools and applications

- Bacterial transcription factors and their targets

  • RNA polymerase and sigma factors
  • Bacterial promoters
  • Nucleoid-associated proteins
  • E. coli transcriptional factors (TF)
  • Identification of TF targets
  • The rpoS regulon

- Regulation of host-pathogen interactions: the example of Toxoplasma gondii

  • Physiopathology
  • Host's factors controlling infection
  • Pathogen's factors influencing infection.


- Analyses of published manuscripts with scientific themes corresponding to the lectures.


- Identification of parasite compartments by indirect immunofluorescence.


- Knowledge in microbial molecular genetics, microbial gene expression, microbial      genomics, host-pathogen interactions, state-of-the-art genomic technologies.

- Ability to analyze biological data from published scientific manuscripts.

- Technical skills in cell biology.


skin.odf-2017:SKIN_ODF_CONTENT_COURSE_INFOS_LIEUX_TITLEGrenoble - Domaine universitaire